San Diego is 70% cheaper than San Francisco.
When comparing San Diego, CA and San Francisco, CA, the overall cost of living indices are 197 and 267 respectively (national median = 100). Rent is $196/month cheaper in San Diego, saving renters about $2,352/year.
Median household income is $37,125/year higher in San Francisco. Home values also differ significantly — the median in San Diego is $848,500 compared to $1,380,500 in San Francisco.
Both cities share the same state tax structure since they are in California.
San Diego vs San Francisco — common questions