Durham and Manchester have a similar cost of living.
When comparing Durham, NC and Manchester, NH, the overall cost of living indices are 105 and 106 respectively (national median = 100). Rent is $53/month cheaper in Durham, saving renters about $636/year.
Median household income is $1,819/year higher in Durham. Home values also differ significantly — the median in Durham is $355,300 compared to $336,300 in Manchester.
New Hampshire has no state income tax, giving Manchester residents a significant tax advantage over North Carolina's 4.5% rate.
Durham vs Manchester — common questions
Other cost of living comparisons for Durham and Manchester