Gainesville and Columbia have a similar cost of living.
When comparing Gainesville, FL and Columbia, SC, the overall cost of living indices are 81 and 80 respectively (national median = 100). Rent is $56/month cheaper in Columbia, saving renters about $672/year.
Median household income is $10,042/year higher in Columbia. Home values also differ significantly — the median in Gainesville is $235,000 compared to $243,500 in Columbia.
Florida has no state income tax, giving Gainesville residents a significant tax advantage over South Carolina's 6.4% rate.
Gainesville vs Columbia — common questions
Other cost of living comparisons for Gainesville and Columbia