San Diego is 50% more expensive than Henderson.
When comparing San Diego, CA and Henderson, NV, the overall cost of living indices are 197 and 131 respectively (national median = 100). Rent is $473/month cheaper in Henderson, saving renters about $5,676/year.
Median household income is $15,667/year higher in San Diego. Home values also differ significantly — the median in San Diego is $848,500 compared to $465,000 in Henderson.
Nevada has no state income tax, giving Henderson residents a significant tax advantage over California's 13.3% rate.
San Diego vs Henderson — common questions
Other cost of living comparisons for San Diego and Henderson