San Diego is 110% cheaper than Santa Clara.
When comparing San Diego, CA and Santa Clara, CA, the overall cost of living indices are 197 and 307 respectively (national median = 100). Rent is $762/month cheaper in San Diego, saving renters about $9,144/year.
Median household income is $69,349/year higher in Santa Clara. Home values also differ significantly — the median in San Diego is $848,500 compared to $1,527,900 in Santa Clara.
Both cities share the same state tax structure since they are in California.
San Diego vs Santa Clara — common questions