San Diego is 15% more expensive than Santa Rosa.
When comparing San Diego, CA and Santa Rosa, CA, the overall cost of living indices are 197 and 172 respectively (national median = 100). Rent is $139/month cheaper in Santa Rosa, saving renters about $1,668/year.
Median household income is $6,911/year higher in San Diego. Home values also differ significantly — the median in San Diego is $848,500 compared to $685,000 in Santa Rosa.
Both cities share the same state tax structure since they are in California.
San Diego vs Santa Rosa — common questions
Other cost of living comparisons for San Diego and Santa Rosa