Denver is 123% more expensive than St. Louis.
When comparing Denver, CO and St. Louis, MO, the overall cost of living indices are 147 and 66 respectively (national median = 100). Rent is $792/month cheaper in St. Louis, saving renters about $9,504/year.
Median household income is $36,402/year higher in Denver. Home values also differ significantly — the median in Denver is $586,700 compared to $185,100 in St. Louis.
Colorado has a lower income tax rate, making Denver slightly more tax-friendly.
Denver vs St. Louis — common questions
Other cost of living comparisons for Denver and St. Louis