Pittsburgh is 15% more expensive than St. Louis.
When comparing Pittsburgh, PA and St. Louis, MO, the overall cost of living indices are 76 and 66 respectively (national median = 100). Rent is $243/month cheaper in St. Louis, saving renters about $2,916/year.
Median household income is $8,858/year higher in Pittsburgh. Home values also differ significantly — the median in Pittsburgh is $193,200 compared to $185,100 in St. Louis.
Pennsylvania has a lower income tax rate, making Pittsburgh slightly more tax-friendly.
Pittsburgh vs St. Louis — common questions
Other cost of living comparisons for Pittsburgh and St. Louis