St. Paul is 38% more expensive than St. Louis.
When comparing St. Paul, MN and St. Louis, MO, the overall cost of living indices are 91 and 66 respectively (national median = 100). Rent is $270/month cheaper in St. Louis, saving renters about $3,240/year.
Median household income is $17,776/year higher in St. Paul. Home values also differ significantly — the median in St. Paul is $280,300 compared to $185,100 in St. Louis.
Missouri has a lower income tax rate, making St. Louis slightly more tax-friendly.
St. Paul vs St. Louis — common questions
Other cost of living comparisons for St. Paul and St. Louis