Durham and St. Petersburg have a similar cost of living.
When comparing Durham, NC and St. Petersburg, FL, the overall cost of living indices are 105 and 106 respectively (national median = 100). Rent is $130/month cheaper in Durham, saving renters about $1,560/year.
Median household income is $6,116/year higher in Durham. Home values also differ significantly — the median in Durham is $355,300 compared to $331,500 in St. Petersburg.
Florida has no state income tax, giving St. Petersburg residents a significant tax advantage over North Carolina's 4.5% rate.
Durham vs St. Petersburg — common questions
Other cost of living comparisons for Durham and St. Petersburg