Houston is 33% more expensive than St. Louis.
When comparing Houston, TX and St. Louis, MO, the overall cost of living indices are 88 and 66 respectively (national median = 100). Rent is $335/month cheaper in St. Louis, saving renters about $4,020/year.
Median household income is $7,615/year higher in Houston. Home values also differ significantly — the median in Houston is $253,400 compared to $185,100 in St. Louis.
Texas has no state income tax, giving Houston residents a significant tax advantage over Missouri's 4.95% rate.
Houston vs St. Louis — common questions
Other cost of living comparisons for Houston and St. Louis