Indianapolis is 12% more expensive than St. Louis.
When comparing Indianapolis, IN and St. Louis, MO, the overall cost of living indices are 74 and 66 respectively (national median = 100). Rent is $134/month cheaper in St. Louis, saving renters about $1,608/year.
Median household income is $7,716/year higher in Indianapolis. Home values also differ significantly — the median in Indianapolis is $207,000 compared to $185,100 in St. Louis.
Indiana has a lower income tax rate, making Indianapolis slightly more tax-friendly.
Indianapolis vs St. Louis — common questions
Other cost of living comparisons for Indianapolis and St. Louis