Mesa is 62% more expensive than St. Louis.
When comparing Mesa, AZ and St. Louis, MO, the overall cost of living indices are 107 and 66 respectively (national median = 100). Rent is $500/month cheaper in St. Louis, saving renters about $6,000/year.
Median household income is $23,500/year higher in Mesa. Home values also differ significantly — the median in Mesa is $364,300 compared to $185,100 in St. Louis.
Arizona has a lower income tax rate, making Mesa slightly more tax-friendly.
Mesa vs St. Louis — common questions
Other cost of living comparisons for Mesa and St. Louis