Minneapolis is 55% more expensive than St. Louis.
When comparing Minneapolis, MN and St. Louis, MO, the overall cost of living indices are 102 and 66 respectively (national median = 100). Rent is $351/month cheaper in St. Louis, saving renters about $4,212/year.
Median household income is $24,990/year higher in Minneapolis. Home values also differ significantly — the median in Minneapolis is $345,600 compared to $185,100 in St. Louis.
Missouri has a lower income tax rate, making St. Louis slightly more tax-friendly.
Minneapolis vs St. Louis — common questions
Other cost of living comparisons for Minneapolis and St. Louis