New York is 152% more expensive than St. Louis.
When comparing New York, NY and St. Louis, MO, the overall cost of living indices are 166 and 66 respectively (national median = 100). Rent is $801/month cheaper in St. Louis, saving renters about $9,612/year.
Median household income is $24,434/year higher in New York. Home values also differ significantly — the median in New York is $751,700 compared to $185,100 in St. Louis.
Missouri has a lower income tax rate, making St. Louis slightly more tax-friendly.
New York vs St. Louis — common questions
Other cost of living comparisons for New York and St. Louis