New York is 57% more expensive than St. Petersburg.
When comparing New York, NY and St. Petersburg, FL, the overall cost of living indices are 166 and 106 respectively (national median = 100). Rent is $237/month cheaper in St. Petersburg, saving renters about $2,844/year.
Median household income is $6,595/year higher in New York. Home values also differ significantly — the median in New York is $751,700 compared to $331,500 in St. Petersburg.
Florida has no state income tax, giving St. Petersburg residents a significant tax advantage over New York's 10.9% rate.
New York vs St. Petersburg — common questions
Other cost of living comparisons for New York and St. Petersburg