Portland is 109% more expensive than St. Louis.
When comparing Portland, OR and St. Louis, MO, the overall cost of living indices are 138 and 66 respectively (national median = 100). Rent is $618/month cheaper in St. Louis, saving renters about $7,416/year.
Median household income is $33,513/year higher in Portland. Home values also differ significantly — the median in Portland is $557,600 compared to $185,100 in St. Louis.
Missouri has a lower income tax rate, making St. Louis slightly more tax-friendly.
Portland vs St. Louis — common questions
Other cost of living comparisons for Portland and St. Louis