San Diego is 198% more expensive than St. Louis.
When comparing San Diego, CA and St. Louis, MO, the overall cost of living indices are 197 and 66 respectively (national median = 100). Rent is $1,245/month cheaper in St. Louis, saving renters about $14,940/year.
Median household income is $49,042/year higher in San Diego. Home values also differ significantly — the median in San Diego is $848,500 compared to $185,100 in St. Louis.
Missouri has a lower income tax rate, making St. Louis slightly more tax-friendly.
San Diego vs St. Louis — common questions
Other cost of living comparisons for San Diego and St. Louis