San Francisco is 234% more expensive than Columbia.
When comparing San Francisco, CA and Columbia, MO, the overall cost of living indices are 267 and 80 respectively (national median = 100). Rent is $1,352/month cheaper in Columbia, saving renters about $16,224/year.
Median household income is $76,958/year higher in San Francisco. Home values also differ significantly — the median in San Francisco is $1,380,500 compared to $268,300 in Columbia.
Missouri has a lower income tax rate, making Columbia slightly more tax-friendly.
San Francisco vs Columbia — common questions
Other cost of living comparisons for San Francisco and Columbia