San Francisco is 281% more expensive than Des Moines.
When comparing San Francisco, CA and Des Moines, IA, the overall cost of living indices are 267 and 70 respectively (national median = 100). Rent is $1,365/month cheaper in Des Moines, saving renters about $16,380/year.
Median household income is $77,480/year higher in San Francisco. Home values also differ significantly — the median in San Francisco is $1,380,500 compared to $183,700 in Des Moines.
Iowa has a lower income tax rate, making Des Moines slightly more tax-friendly.
San Francisco vs Des Moines — common questions
Other cost of living comparisons for San Francisco and Des Moines