San Francisco is 124% more expensive than Lowell.
When comparing San Francisco, CA and Lowell, MA, the overall cost of living indices are 267 and 119 respectively (national median = 100). Rent is $816/month cheaper in Lowell, saving renters about $9,792/year.
Median household income is $65,241/year higher in San Francisco. Home values also differ significantly — the median in San Francisco is $1,380,500 compared to $395,100 in Lowell.
Massachusetts has a lower income tax rate, making Lowell slightly more tax-friendly.
San Francisco vs Lowell — common questions
Other cost of living comparisons for San Francisco and Lowell