San Francisco is 338% more expensive than Rochester.
When comparing San Francisco, CA and Rochester, NY, the overall cost of living indices are 267 and 61 respectively (national median = 100). Rent is $1,380/month cheaper in Rochester, saving renters about $16,560/year.
Median household income is $94,818/year higher in San Francisco. Home values also differ significantly — the median in San Francisco is $1,380,500 compared to $120,600 in Rochester.
New York has a lower income tax rate, making Rochester slightly more tax-friendly.
San Francisco vs Rochester — common questions
Other cost of living comparisons for San Francisco and Rochester