San Francisco is 55% more expensive than Santa Rosa.
When comparing San Francisco, CA and Santa Rosa, CA, the overall cost of living indices are 267 and 172 respectively (national median = 100). Rent is $335/month cheaper in Santa Rosa, saving renters about $4,020/year.
Median household income is $44,036/year higher in San Francisco. Home values also differ significantly — the median in San Francisco is $1,380,500 compared to $685,000 in Santa Rosa.
Both cities share the same state tax structure since they are in California.
San Francisco vs Santa Rosa — common questions
Other cost of living comparisons for San Francisco and Santa Rosa