Santa Ana is 147% more expensive than St. Louis.
When comparing Santa Ana, CA and St. Louis, MO, the overall cost of living indices are 163 and 66 respectively (national median = 100). Rent is $997/month cheaper in St. Louis, saving renters about $11,964/year.
Median household income is $33,075/year higher in Santa Ana. Home values also differ significantly — the median in Santa Ana is $657,800 compared to $185,100 in St. Louis.
Missouri has a lower income tax rate, making St. Louis slightly more tax-friendly.
Santa Ana vs St. Louis — common questions
Other cost of living comparisons for Santa Ana and St. Louis