St. Louis is 18% cheaper than Columbia.
When comparing St. Louis, MO and Columbia, SC, the overall cost of living indices are 66 and 80 respectively (national median = 100). Rent is $180/month cheaper in St. Louis, saving renters about $2,160/year.
Median household income is $374/year higher in Columbia. Home values also differ significantly — the median in St. Louis is $185,100 compared to $243,500 in Columbia.
Missouri has a lower income tax rate, making St. Louis slightly more tax-friendly.
St. Louis vs Columbia — common questions
Other cost of living comparisons for St. Louis and Columbia