St. Louis is 14% more expensive than Jackson.
When comparing St. Louis, MO and Jackson, MS, the overall cost of living indices are 66 and 58 respectively (national median = 100). Rent is comparable in both cities, with less than $50/month separating them.
Median household income is $12,041/year higher in St. Louis. Home values also differ significantly — the median in St. Louis is $185,100 compared to $108,200 in Jackson.
Missouri has a lower income tax rate, making St. Louis slightly more tax-friendly.
St. Louis vs Jackson — common questions
Other cost of living comparisons for St. Louis and Jackson