St. Louis and Mobile have a similar cost of living.
When comparing St. Louis, MO and Mobile, AL, the overall cost of living indices are 66 and 66 respectively (national median = 100). Rent is $51/month cheaper in St. Louis, saving renters about $612/year.
Median household income is $4,189/year higher in St. Louis. Home values also differ significantly — the median in St. Louis is $185,100 compared to $170,300 in Mobile.
Missouri has a lower income tax rate, making St. Louis slightly more tax-friendly.
St. Louis vs Mobile — common questions
Other cost of living comparisons for St. Louis and Mobile