Washington is 159% more expensive than St. Louis.
When comparing Washington, DC and St. Louis, MO, the overall cost of living indices are 171 and 66 respectively (national median = 100). Rent is $922/month cheaper in St. Louis, saving renters about $11,064/year.
Median household income is $51,008/year higher in Washington. Home values also differ significantly — the median in Washington is $724,600 compared to $185,100 in St. Louis.
Missouri has a lower income tax rate, making St. Louis slightly more tax-friendly.
Washington vs St. Louis — common questions
Other cost of living comparisons for Washington and St. Louis