San Francisco is 338% more expensive than Buffalo.
When comparing San Francisco, CA and Buffalo, NY, the overall cost of living indices are 267 and 61 respectively (national median = 100). Rent is $1,430/month cheaper in Buffalo, saving renters about $17,160/year.
Median household income is $93,396/year higher in San Francisco. Home values also differ significantly — the median in San Francisco is $1,380,500 compared to $152,300 in Buffalo.
New York has a lower income tax rate, making Buffalo slightly more tax-friendly.
San Francisco vs Buffalo — common questions
Other cost of living comparisons for San Francisco and Buffalo