St. Louis is 8% more expensive than Buffalo.
When comparing St. Louis, MO and Buffalo, NY, the overall cost of living indices are 66 and 61 respectively (national median = 100). Rent is comparable in both cities, with less than $50/month separating them.
Median household income is $7,229/year higher in St. Louis. Home values also differ significantly — the median in St. Louis is $185,100 compared to $152,300 in Buffalo.
Missouri has a lower income tax rate, making St. Louis slightly more tax-friendly.
St. Louis vs Buffalo — common questions
Other cost of living comparisons for St. Louis and Buffalo